Low-intensity pulsed ultrasound inhibits messenger rna expression of matrix metalloproteinase-13 induced by interleukin-1 βeta in intensity-dependent manner on chondrocytes
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چکیده
منابع مشابه
Low Intensity Pulsed Ultrasound (LIPUS)
The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...
متن کاملLow Intensity Pulsed Ultrasound (LIPUS)
The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W/cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...
متن کاملLOW INTENSITY PULSED ULTRASOUND TREATMENT INCREASES RABBIT RADIAL FRACTURE HEALING
In order to study the effect of ultrasound (US) on bone healing, a complete transverse fracture was made in the right radius of adult male rabbits by a cutter. 52 rabbits were used: group I. control (n= 17): group 2. test (n:=: 15): group 3, intact (n= I) and group 4 (n= 12) who were examined only for evaluation of the cutter effects in detail. 7 animals were operated with a Gigli saw. The ...
متن کاملThe triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes
A synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO), has been reported to have anti-inflammatory properties and to decrease the interleukin-1 (IL-1)-induced expression of matrix metalloproteinase-1 (MMP-1) and MMP-13. We have shown previously that IL-1 induces expression of the inhibitor of NF-kappaB (IkappaB) family member Bcl-3, and that this contributes to MMP-1 exp...
متن کاملEffects of low-intensity pulsed ultrasound and hyperbaric oxygen on human osteoarthritic chondrocytes
BACKGROUND Although the individual effects of hyperbaric oxygen (HBO) and low-intensity pulsed ultrasound (LIPUS) on osteoarthritic (OA) chondrocytes have been reported, the effects of HBO combined with LIPUS treatment are unknown. METHODS OA chondrocytes were obtained from patients undergoing knee replacement surgery. RNA was isolated for real-time polymerase chain reaction (PCR) analysis of...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2012
ISSN: 1063-4584
DOI: 10.1016/j.joca.2012.02.408